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KMID : 1103920120180020163
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Korean Journal of Hepatology
2012 Volume.18 No. 2 p.163 ~ p.173
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Clinical applications of transient elastography
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Jung Kyu-Sik
Kim Seung-Up
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Abstract
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Chronic liver disease represents a major public health problem, accounting for significant morbidity and mortality worldwide. As prognosis and management depend mainly on the amount and progression of liver fibrosis, accurate quantifi cation of liver fi brosis is essential for therapeutic decision-making and follow-up of chronic liver diseases. Even though liver biopsy is the gold standard for evaluation of liver fi brosis, non-invasive methods that could substitute for invasive procedures have been investigated during past decades. Transient elastography (TE, FibroScan®) is a novel non-invasive method for assessment of liver fi brosis with chronic liver disease. TE can be performed in the outpatient clinic with immediate results and excellent reproducibility. Its diagnostic accuracy for assessment of liver fibrosis has been demonstrated in patients with chronic viral hepatitis; as a result, unnecessary liver biopsy could be avoided in some patients. Moreover, due to its excellent patient acceptance, TE could be used for monitoring disease progression or predicting development of liver-related complications. This review aims at discussing the usefulness of TE in clinical practice.
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KEYWORD
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Chronic liver disease, Cirrhosis, Decompensation, Fibroscan, Fibrosis, Hepatocellular carcinoma, Liver stiff ness measurement, Transient elastography
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